Side Effects

Hydrocortisone Cream Side Effects

Hydrocortisone cream is commonly used for its anti-inflammatory properties, but it may cause several side effects, especially with prolonged or inappropriate use[1]:

  • Common side effects include skin redness, itching, stinging, rash, burning, dryness, or other irritation of the treated area, and inflamed hair follicles[1][3][7].
  • You might notice changes in the appearance or color of the treated skin, acne, unwanted hair growth, or tiny bumps, especially around the mouth[1][3][5].
  • More serious allergic reactions can occur, such as hives, swelling of the face or throat, difficulty breathing, or severe skin rash. These reactions require immediate medical attention[1][3].
  • Extended or excessive use can cause thinning of the skin, stretch marks, delayed wound healing, or increased risk of skin infections at the application site[1][2][3][5].
  • Other potential complications involve lighter or darker patches on the skin (pigmentation changes) and, in children, possible slowed growth and delayed weight gain[1][2][5].
  • Rarely, systemic absorption (especially with prolonged use or on large areas) can lead to symptoms such as weight gain, swelling (mainly of the face), increased body or facial hair, irregular menstrual periods, and mood or memory changes[1].

Precautions to minimize risks:

  • Use hydrocortisone only as directed, on affected areas, and not for prolonged periods without medical advice[2].
  • Avoid applying near the eyes or on the face unless explicitly instructed by a healthcare professional[2][6].
  • Children may absorb more medication and are more prone to side effects; consult a healthcare provider before use in children[1][5].
  • Report any persistent, worsening, or unusual symptoms to your doctor promptly[3][5].

References

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