Soursop (also known as graviola) can cause several side effects, particularly when consumed excessively or over the long term.[1] Potential risks are especially notable for the nervous system, pregnancy, drug interactions, liver and kidney health, and allergic reactions.
- Neurotoxicity: Soursop contains annonacin and acetogenins, compounds that can damage nerve cells, potentially leading to movement disorders similar to Parkinson’s disease. High consumption has been linked to increased rates of atypical parkinsonism, especially in some Caribbean populations.[1][2][4][6][7]
- Liver and Kidney Damage: Excessive intake of soursop leaves or products has been associated with risk of hepatotoxicity and nephrotoxicity (liver and kidney damage), particularly with chronic use.[3][7]
- Pregnancy and Breastfeeding: Soursop may stimulate uterine contractions and is not considered safe during pregnancy or breastfeeding. It may reduce milk production and potentially harm fetal or infant development. Birth defects and other adverse effects have been reported in animal studies.[1][2][3][5]
- Drug Interactions: Soursop can interact with medications for high blood pressure, diabetes, depression, and blood thinners (anticoagulants), potentially intensifying or reducing their effects. People on these medications should consult a healthcare provider first.[2][3][5][7]
- Blood Pressure and Blood Sugar: Soursop may lower blood pressure and blood sugar, which can be dangerous for people with hypotension, diabetes, or those taking antihypertensive or antidiabetic medications.[3][5][7]
- Digestive Symptoms: Excessive soursop consumption can cause nausea, vomiting, diarrhea, and intestinal discomfort.[5]
- Allergy and Latex Sensitivity: Allergic reactions, including latex sensitivity, may occur in some individuals. Symptoms include itching, swelling, or rash.[1]
- Effects on Children: There is insufficient evidence about safety in children, so soursop is not recommended for them.[5]
Soursop is best consumed sparingly and not recommended for individuals with specific medical conditions (such as Parkinson’s or liver/kidney disease), pregnant or breastfeeding women, children, or those taking interacting medications.[3][5][7] Always consult a healthcare professional before adding soursop to your diet.
References
- [1] Soursop Side Effects What You Need To Know Before …
- [2] 7 Benefits and side effects of soursop tea
- [3] Soursop (Graviola): Benefits, Tea Recipe, Nutrition & Side …
- [4] The Health Benefits and Risks of Soursop: An In-Depth Look …
- [5] Soursop Tea: How to Make It, 10 Benefits & Side Effects
- [6] Why Experts Warn Against Soursop for Cancer Treatment
- [7] Graviola (soursop) | Complementary and alternative therapy