Atroiza is a combination antiretroviral pill used to treat HIV, containing efavirenz, emtricitabine, and tenofovir disoproxil fumarate[2]. Like its branded counterpart Atripla, Atroiza can produce a range of side effects, most of which are related to the efavirenz component[7].
Common side effects of Atroiza may include:
- Dizziness, headache, difficulty sleeping, abnormal dreams, and drowsiness[1][3][6].
- Nausea, vomiting, diarrhea, stomach pains, and feeling bloated[1][3].
- Rash, which can sometimes be severe; some rashes, such as Stevens-Johnson syndrome, are potentially life-threatening and require immediate medical attention if blistering occurs on skin or mucous membranes[1][6].
- Fatigue or tiredness[1].
- Mood changes, including depression, feeling anxious, or unusual dreams[1][6][7].
- Difficulty concentrating and weakness[3].
Serious potential side effects (seek medical advice promptly):
- Severe skin reactions (including painful blistering rash or peeling skin)[1].
- Liver damage or hepatotoxicity, which may show as yellowing of eyes or skin, dark urine, abdominal pain, or persistent nausea[1].
- Depression, suicidal thoughts, or severe mood changes[6][7].
- Kidney problems or changes in kidney function, sometimes detected on blood tests[3].
- Changes in cholesterol, liver, or kidney blood test results[3].
Most side effects, especially those related to sleep or mood, are more common when starting treatment and often decrease within two to four weeks[3]. If side effects are severe or persistent, or if new symptoms appear, it is important to contact a healthcare provider to discuss management or possible changes to the treatment regimen[5].
References
- [1] Efavirenz/Emtricitabine/Tenofovir Disoproxil Fumarate – WebMD
- [2] What is Atroiza used for? – HIV i-Base
- [3] Efavirenz/emtricitabine/tenofovir disoproxil fumarate – aidsmap
- [5] Antiretroviral HIV Drugs: Side Effects and Adherence – Healthline
- [6] Efavirenz – Wikipedia
- [7] Atripla / TLE (efavirenz + tenofovir DF + emtricitabine/lamivudine) – i-Base
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