Vorellix 10mg contains vortioxetine, which is commonly prescribed to treat major depressive disorder. The most common side effects include nausea, constipation, vomiting, and dry mouth. Nausea is usually dose-related, often appears during the first week of treatment, and may subside over time, but can persist in some patients[3][5].
- Nausea (up to 42% of patients in some studies)
- Constipation (up to 15%)
- Vomiting
- Dry mouth
- Diarrhea
- Sexual dysfunction (decreased libido, delayed or absent orgasm or ejaculation, more common in males but can occur in all sexes)
- Dizziness
- Unusual dreams
- Headache
Serious side effects can also occur, such as:
- Rash, hives, itching, or swelling (especially of the eyes, face, lips, tongue, or throat)
- Difficulty breathing or swallowing
- Fever, sweating, confusion, fast or irregular heartbeat, muscle stiffness or twitching, agitation, hallucinations (potential serotonin syndrome)
- Unusual bruising or bleeding
- Memory problems, difficulty concentrating, confusion
- Seizures or loss of consciousness
There is a boxed warning regarding an increased risk of suicidal thoughts or actions in patients under 24 years old, especially during the first few months of treatment or when the dose changes. Close monitoring for mood or behavior changes is recommended[1][4][5].
Patients should not stop taking vortioxetine abruptly without medical supervision, as withdrawal symptoms like irritability, dizziness, nausea, vomiting, headaches, and abnormal sensations may occur[2].