LTD pills usually refer to a combination medication containing dolutegravir and lamivudine, commonly prescribed for the treatment of HIV infection. Both drugs may cause side effects ranging from mild to serious. Common and serious side effects are listed below.
- Headache[5]
- Nausea[1][3][5][7]
- Diarrhea[1][3][5][7]
- Gas or bloating[5][7]
- Difficulty sleeping (insomnia)[3][5][7]
- Fatigue or tiredness[1][3][5][7]
- Dizziness[5][7]
- Abdominal discomfort or pain[1][3][5][7]
- Vomiting[1][3][5][7]
- Muscle weakness or muscle pain[1][5]
- Elevated liver enzymes (may present as yellowing of skin/eyes, dark urine, light-colored stools, upper right abdominal pain, loss of appetite)[5][7]
- Mood changes or anxiety[5]
Serious side effects that require immediate medical attention, though less common, can include:
- Allergic reactions such as rash, hives, swelling of the face/lips/tongue/throat, difficulty breathing or swallowing[5][7]
- Severe liver problems (yellow eyes or skin, dark urine, light-colored stool, upper abdominal pain, loss of appetite, nausea, vomiting)[5][7]
- Severe fatigue, muscle pain, or weakness especially with difficulty breathing or irregular heartbeat[5]
- Blistering or peeling skin, mouth sores, red or swollen eyes[5][7]
Most side effects are mild and temporary but some may require discontinuation of therapy or urgent medical attention. Always notify your healthcare provider if you experience any persistent or severe symptoms while taking LTD pills.