Duphaston, which contains dydrogesterone, can cause a range of side effects. Common side effects include breast tenderness, headaches, nausea, abdominal pain, dizziness, mood swings, and menstrual irregularities[1][2][3][4][5][7]. Some people may also experience drowsiness, dry mouth, and acne[1][5]. Serious but less common side effects may involve abnormal vaginal bleeding, stomach pain, or allergic reactions such as rashes and swelling[2][4].
When Duphaston is used with estrogen (as in hormone replacement therapy), there is an increased risk of heart attacks, stroke, breast cancer, blood clots, and possibly dementia in women over 65[1]. Duphaston is not recommended if you are allergic to peanuts, have unusual vaginal bleeding, a history of certain cancers, or specific rare metabolic disorders[1]. Caution is also advised for people with a history of heart disease, liver or kidney problems, epilepsy, asthma, diabetes, migraine, endometriosis, lupus, or thyroid conditions[1].
Duphaston is generally unsafe for children under 12 years old[1]. If you experience severe or persistent side effects, you should seek medical advice promptly[2][4].
References
- [1] Duphaston 10 mg Tablet | Uses, Side Effects, Price – Apollo Pharmacy
- [2] Duphaston (Dydrogesterone) Uses and Safety Information – Medicover Hospitals
- [3] Dydrogesterone – Wikipedia
- [4] Dydrogesterone – HealthHub
- [5] Duphaston Tablet: Uses, Side Effects, Price & Substitutes – Truemeds
- [7] What are the side effects of Dydrogesterone? – Patsnap Synapse
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