Dormonoct 2mg (containing loprazolam) is used primarily for the short-term treatment of insomnia. As with other benzodiazepines, it has a range of possible side effects:
- Drowsiness (especially in the elderly or those receiving high doses)[1]
- Over-sedation[1]
- Mood depression and emotional blunting[1]
- Disorientation or confusion[1][3][5]
- Lethargy or lack of energy[1]
- Ataxia (clumsiness, lack of coordination, balance issues)[1][3][5]
- Muscle weakness[3][5]
- Memory impairment or anterograde amnesia (loss of memory for events after taking the drug)[1][3][5][7]
- Paradoxical reactions such as agitation or aggression[1][3][5]
- Gastrointestinal disturbances (nausea, constipation, diarrhea)[1][3]
- Headache[3][7]
- Vertigo, lightheadedness, or dizziness[3][5][7]
- Visual disturbances[3]
- Salivation changes[3]
- Changes in libido (sexual drive)[1][3]
- Incontinence or urinary retention[3]
- Blood disorders and jaundice (yellowing of skin and eyes)[1][3]
- Skin reactions[3]
Serious allergic reactions, such as jaundice (yellowing of skin and eyes), can occur and may require urgent medical attention[1][3].
Dependency, withdrawal, and tolerance:
- Dormonoct can cause physical and psychological dependence, especially when used at high doses or for longer than recommended. Withdrawal symptoms (including convulsions) may appear if stopped abruptly[1][3].
- Paradoxically, it may increase agitation or aggression in some individuals[1][3].
- Tolerance and decreased effectiveness can develop if used for more than 2-4 weeks[3].
Other commonly reported patient experiences include morning grogginess, problems concentrating, sleepiness, and headaches[7].
Elderly patients are more sensitive to these side effects, including heightened risk of falls, confusion, and memory problems[1][3][5].
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