When choosing anxiety medications with the least side effects, it’s important to remember that everybody reacts to medications differently, and what works well with minimal effects for one person may not be the same for another[1]. However, some medications are generally considered to be well-tolerated or associated with fewer side effects for many people.
- SSRIs (Selective Serotonin Reuptake Inhibitors): Medications like citalopram (Celexa), escitalopram (Lexapro), sertraline (Zoloft), and fluoxetine (Prozac) are usually prescribed first and are known for comparatively mild and manageable side effects. Among SSRIs, citalopram and escitalopram are often highlighted as among the best-tolerated[3][7]. Common side effects can include nausea, headache, and insomnia but these often subside over time.
- Buspirone (Buspar): This medication is non-addictive and generally causes fewer side effects than SSRIs and SNRIs. The most common are mild, such as lightheadedness or nausea. It specifically targets one serotonin receptor, possibly resulting in fewer side effects compared to medications that affect several receptors[1][3][5].
- Bupropion (Wellbutrin): This is an antidepressant that is less likely to cause weight gain or sexual side effects and is sometimes used for anxiety. However, it’s not suitable for everyone, especially those prone to seizures[1][3].
- Beta-Blockers (e.g., Propranolol): These are not traditional anxiety medications but can help with physical symptoms of anxiety such as rapid heartbeat or tremors. They are especially useful for situational anxiety (like public speaking) and have a mild side effect profile for most people[2][5].
- Hydroxyzine (Vistaril): This antihistamine can be used short-term for anxiety and is unlikely to be habit-forming, with side effects generally limited to drowsiness and dry mouth[5].
Benzodiazepines (such as Xanax or Valium) are effective and generally well tolerated in the short term, but they carry a significant risk of dependence and withdrawal, so they are not recommended for long-term use[1][2][6].
Some people also choose natural supplements, such as L-Theanine, magnesium, or chamomile, for milder anxiety. However, their efficacy is less documented and regulation is inconsistent. Always consult with a healthcare professional before starting any supplement, as these can interact with other medications[2][4].
Ultimately, the best choice depends on your medical and psychological history and should be made with guidance from a healthcare provider.
References
- [1] What Is The “Safest” Drug for Anxiety? – Calm Clinic
- [2] What Are Some Alternatives to Benzodiazepines for Anxiety?
- [3] What Is the Best Anxiety Medication with Less Side Effects?
- [4] 7 Xanax Alternatives: How Else You Can Help Treat Your Anxiety
- [5] 5 Non-Addictive Anxiety Medications – Washburn House
- [6] Alternatives to Benzodiazepines for Anxiety: What Works?
- [7] Which SSRIs Have the Least Side Effects? 4 Options – GoodRx
Leave a Reply