ADCO-CONTROMET tablet (containing metoclopramide) can cause a range of side effects, from common and mild to serious and potentially persistent.[2]
Common side effects include:
- Sleepiness or drowsiness
- Lack of energy
- Low mood or depression
- Dizziness or feeling faint (low blood pressure)
- Diarrhea
- Fatigue
- Confusion or insomnia
- Headache
These side effects are usually mild and often go away on their own. If they persist or become bothersome, consult your healthcare provider.[5][7]
Serious side effects of ADCO-CONTROMET/Metoclopramide, warranting immediate medical attention, include:
- Tardive dyskinesia (involuntary, repetitive movements, often of the face or limbs; may be irreversible), especially with long-term use or in the elderly and women
- Extrapyramidal symptoms (muscle rigidity, tremors, restlessness, dystonia)
- Neuroleptic malignant syndrome (high fever, muscle rigidity, confusion, rapid heart rate)
- Depression or thoughts of self-harm
- Parkinsonism (shaking, stiffness, slow movement, balance problems)
- Allergic reactions (rash, swelling of face/tongue/throat, difficulty breathing)
- Hyperprolactinemia (high levels of prolactin, potentially causing menstrual problems in women or breast enlargement in men)
- Hallucinations
Chronic treatment or doses exceeding 12 weeks significantly increase the risk of serious side effects like tardive dyskinesia. The elderly, especially elderly women, are most at risk. In many cases, symptoms of tardive dyskinesia may lessen or resolve after stopping the drug, but some cases may be permanent.[2][3][5][7]
Withdrawal symptoms after discontinuation can include dizziness
ADCO-CONTROMET (metoclopramide) tablets can cause a range of side effects, from mild to serious.[2]
Common side effects:
- Feeling sleepy or tired
- Low mood or mild depression
- Dizziness or faintness (low blood pressure)
- Diarrhoea
- Fatigue
- Confusion or insomnia
- Headache
These effects are usually mild and tend to get better within a few days. If symptoms persist, consult a healthcare provider.[5][7]
Serious side effects (seek medical attention):
- Tardive dyskinesia (repetitive, involuntary movements, especially of the face and limbs; can be irreversible, especially with long-term use or in elderly)
- Extrapyramidal symptoms (muscle rigidity, tremors, restlessness, abnormal movements)
- Neuroleptic malignant syndrome (high fever, stiff muscles, confusion, rapid heart rate)
- Severe depression or thoughts of suicide
- Parkinsonism (shaking, slow movement, stiffness, balance problems)
- Allergic reactions (rash, swelling of face, tongue, lips, or throat, difficulty breathing)
- Hyperprolactinaemia (elevated prolactin: menstrual problems, breast enlargement in men)
- Hallucinations
Chronic or high-dose treatment, or use longer than 12 weeks, increases risk of serious side effects, particularly tardive dyskinesia, which may not disappear even after discontinuation. The elderly, especially women, are at highest risk.[2][3][5][7]
If you experience withdrawal symptoms (dizziness, nervousness, headaches) after stopping ADCO-CONTROMET, report them to your doctor.[7]
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