Ovral 28

Ovral 28 Side Effects

Ovral 28 is a combination oral contraceptive pill that contains both estrogen and progestin. It is widely used for preventing pregnancy, regulating menstrual cycles, and treating various hormonal disorders. Like all medications, Ovral 28 can cause side effects in some individuals. It’s important to be aware of these potential side effects to make an informed decision about your health.

Common Side Effects

Many women taking Ovral 28 may experience mild side effects that often diminish as the body adjusts to the medication. Common side effects include:

  1. Nausea and Vomiting: This is a typical side effect during the first few months of use.
  2. Breast Tenderness: Some women may notice increased sensitivity or discomfort in their breasts.
  3. Headaches: Mild headaches or migraines can occur, particularly during the initial stages of use.
  4. Weight Gain: Some users report slight weight gain due to fluid retention.
  5. Mood Changes: Emotional fluctuations, including mood swings and depression, can occur.
  6. Spotting or Breakthrough Bleeding: Irregular bleeding between periods may be experienced, especially during the first few cycles.
  7. Decreased Libido: A reduction in sexual desire is possible for some women.

Serious Side Effects

While serious side effects are less common, they can occur. It’s crucial to seek medical attention if you experience any of the following:

  1. Blood Clots: Symptoms may include sudden severe headaches, vision changes, chest pain, shortness of breath, and leg pain or swelling.
  2. High Blood Pressure: Regular monitoring of blood pressure is recommended while on Ovral 28.
  3. Liver Problems: Look out for symptoms such as jaundice (yellowing of the skin or eyes), severe abdominal pain, or dark urine.
  4. Severe Mood Changes: Intense mood swings, depression, or anxiety should be reported to a healthcare provider immediately.
  5. Breast Lumps: Any new or unusual lumps in the breast should be evaluated by a doctor.
  6. Allergic Reactions: Symptoms include hives, difficulty breathing, and swelling of the face, lips, tongue, or throat.

Long-Term Use and Risks

Long-term use of Ovral 28 can carry additional risks. It’s important to discuss these with your healthcare provider to weigh the benefits and risks based on your medical history and personal health goals.

  1. Cardiovascular Risks: Long-term use can increase the risk of heart attack, stroke, and blood clots, especially in smokers and women over 35.
  2. Cancer Risks: There is a slightly increased risk of breast and cervical cancer with prolonged use, although the risk of ovarian and endometrial cancers may be reduced.

Who Should Avoid Ovral 28?

Certain individuals should not take Ovral 28 due to the increased risk of severe side effects. These include women with:

  1. History of Blood Clots: Women who have had blood clots, stroke, or heart attack.
  2. Certain Cancers: Those with a history of breast, uterine, or liver cancer.
  3. Uncontrolled Hypertension: Women with poorly managed high blood pressure.
  4. Severe Migraines: Especially migraines with aura, as they can increase the risk of stroke.
  5. Liver Disease: Women with active liver disease or liver tumors.

While Ovral 28 is an effective contraceptive method, it’s essential to be aware of its potential side effects. Regular check-ups with your healthcare provider can help monitor any adverse effects and ensure that Ovral 28 remains a safe option for you. For more detailed information on side effects of various medications, visit Side Effects.


By understanding both the common and serious side effects associated with Ovral 28, you can make informed decisions about your contraceptive options and overall health. If you have any concerns or experience unusual symptoms, consult your healthcare provider promptly.

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