Celestamine Side Effects

Overview

Celestamine is a medication that combines betamethasone, a corticosteroid, and dexchlorpheniramine, an antihistamine. It is commonly prescribed for the treatment of allergic reactions, inflammatory conditions, and other related disorders. This article explores the verified side effects of Celestamine, providing essential information for South African users, including safety warnings, and important considerations.

Verified Side Effects

Common Side Effects

Celestamine, like many medications, can cause several common side effects due to its active ingredients:

• Weight gain: As reported by MedicineNet, corticosteroids like betamethasone can cause fluid retention and weight increase.
• Increased appetite
• Nausea and vomiting
• Drowsiness and dizziness: Dexchlorpheniramine is an antihistamine that can cause sedation and drowsiness, as detailed by Healthline.
• Dry mouth: Likely due to the antihistamine component.

Less Common Side Effects

• Upset stomach
• Difficulty sleeping
• Blurred vision
• Nervousness

Serious Side Effects

According to Mayo Clinic, more serious side effects may require immediate medical attention:

• Mood changes: Such as depression or euphoria caused by corticosteroids.
• High blood pressure and increased risk of infections.
• Allergic reactions: Including rash, itching, and swelling, detailed by the FDA.
• Muscle weakness or seriously high blood sugar levels.

Rare Side Effects

While rare, prolonged usage can lead to:

• Osteoporosis
• Cataracts and glaucoma
• Peptic ulcer disease

Safety Warnings

Patients should be aware that long-term use of corticosteroids like betamethasone can suppress the immune system, increasing susceptibility to infections. It’s crucial to follow prescribed doses and to discuss with a physician before making any changes.

When to Seek Medical Attention

Immediate medical support should be sought if any severe reactions occur, such as:

• Difficulty breathing or swelling, indicating a possible allergic reaction.
• Severe mood swings or psychological symptoms.
• High blood pressure symptoms like severe headache or blurred vision.

Contraindications

Celestamine should not be used in individuals with known hypersensitivity to betamethasone, dexchlorpheniramine, or other similar components. Patients with systemic fungal infections or those receiving live vaccines should also avoid it, as noted by SAHPRA.

Interactions

Significant drug interactions may occur when Celestamine is combined with certain medications:

• Blood thinners: Can increase bleeding risk.
• Diabetes medications: May require dose adjustment due to altered blood sugar levels.
• NSAIDs and alcohol: Can increase gastrointestinal irritation.

Guidelines Relevant to South African Users

South African authorities, like the South African Health Products Regulatory Authority (SAHPRA), emphasize adhering to prescribed guidelines and consulting healthcare professionals regarding potential interactions and prolonged use concerns.

In conclusion, while Celestamine is beneficial for treating allergic and inflammatory conditions, awareness of its side effects and safety guidelines is crucial. Always consult healthcare professionals for personalized advice and before making any changes to your medication regimen.